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History
The
patient is a 50-year-old male who had undergone a left total hip
replacement in 1980 for osteoarthritis. Two years later, he underwent
revision of the acetabular component because of loosening. He
then did well until several months ago, when he began to develop
increasing pain in the left hip. His primary orthopaedic surgeon
diagnosed massive acetabular osteolysis with loosening of the
acetabular component of his prosthesis and he was referred for
further management. Past medical history is notable for IV drug
use approximately 20 years ago. He also had a history of ethanol
abuse but had not consumed any alcohol for the past 12 years.
The patient has no other active medical issues.
Physical
Examination
On
examination, the patient had a marked Trendelenburg limp on the
left. The left lower extremity was approximately 2.5cm shorter
than the right. On range of motion testing, the left hip had 95
degrees of flexion, no internal rotation, 30 degrees external
rotation, and 20 degrees of abduction. Neurovascular examination
of both lower extremities was normal.
Radiology
Studies
AP
(Figure 1) and lateral (Figure 2) views of the left hip reveal
massive osteolysis about the acetabular component, which consists
of a cage with cemented polyethylene liner. The component has
migrated superiorly and is in significant protrusio. The femoral
stem appears to be well fixed.
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Figure 1
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Figure 2
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Diagnosis
Massive
osteolysis of left acetabulum with loosening of prosthesis
Discussion
Revision
of a loose acetabular component can present a challenging surgical
problem, particularly if there is significant bone loss. Several
classification systems have been developed as guides to treatment.
The AAOS classification system [4] categorizes defects as either
segmental, cavitary, or combined, with pelvic discontinuity and
bony ankylosis added as additional categories. The classification
system of Paprosky et al [7] is more complex but is more
useful for determining the approach to treatment. This system
depends on four radiographic parameters: superior migration of
the hip center, ischial lysis (indicative of posterior column
insufficiency), destruction of the teardrop (medial wall), and
disruption of Kohlers line. The present case illustrates
all of these features and would be classified as Type IIIB, the
most severe, using this system.
When
performing an acetabular revision, the femoral component must
be examined for stability and alignment. If the component is well
fixed and not malpositioned, it may be left in place and only
the acetabular component revised. Good clinical results have been
reported with retention of a well-fixed femoral component during
isolated acetabular revision [5].
One
of the challenges in a case such as this is constructing an adequate
superior buttress to support the new acetabular component. One
option is to use a structural allograft, which is fixed to the
pelvis and then reamed to accommodate a jumbo uncemented cup [6].
Alternatively, the defect can be spanned by a cage or ring [1];
morsellized bone graft is packed beneath the device and a polyethylene
liner is cemented into it. Finally, an uncemented cup can be buttressed
superiorly by additional metal. While oblong cups have been developed
for this purpose, a more flexible approach is to use a cup with
modular augments (as was done in the present case).
Porous
tantalum is a relatively new biomaterial which has been used to
fabricate acetabular components for both primary and revision
arthroplasty applications. Currently manufactured by the Zimmer
Corporation under the name Trabecular Metal, the material
is formed by precipitation of elemental tantalum metal onto a
carbon skeleton which approximates the morphology of cancellous
bone [8]. The material is highly porous (75-85% by volume) but
has sufficient mechanical strength to provide support for an acetabular
component [8]. In a canine model, porous tantalum has been shown
to reproducibly develop 40-50% bone ingrowth within 4 weeks of
implantation [2,3]. For revision applications, acetabular cups
as well as modular augments in a variety of sizes are available.
The augments are cemented to the cup prior to implantation; both
the cups and augments contain multiple holes to allow supplemental
screw fixation as well.
The
main theoretical advantage of porous tantalum implants is that
they stimulate true bone ingrowth into the material (due
to its trabecular morphology) rather than ongrowth
onto the surface as with conventional cementless cups. The main
disadvantage of using porous tantalum augments instead of bulk
allograft is that the material is not replaced by bone. If removal
of the component is required during a subsequent revision, this
will create a new bony defect.
Clinical
Course
It
was recommended to the patient that he undergo revision of his
acetabular component. Because of the large osteolytic defect,
the preoperative plan was to use either a bulk allograft, a Burch-Schneider
ring with cemented liner, or a jumbo cup with possible augmentation
in order to reconstruct the acetabulum. The risks of the procedure,
including sciatic nerve injury, infection, dislocation, and graft
resorption, were discussed with the patient and he elected to
proceed.
The
hip was approached via a direct lateral approach, using the previous
skin incision. Once the hip capsule was entered, the acetabular
component was found to be grossly loose and was easily removed.
The femoral stem was solidly fixed and in acceptable alignment
and thus was not revised. Intraoperative soft-tissue specimens
were sent for frozen-section analysis and revealed no sign of
infection. Thus, the decision was made to proceed with the revision
arthroplasty.
With
the acetabular component removed, the lytic defect was debrided
and carefully examined. Overall, the defect measured approximately
10cm in largest diameter. A large superior dome defect was present,
as well as a small medial wall defect. Because a portion of both
the anterior and posterior columns were still intact, it was felt
that a jumbo cup might gain sufficient purchase, supplemented
by an augment superiorly as well as multiple screws.
A
70mm acetabular component composed of porous tantalum (trabecular
metal) was found to fit well, with a 58x20mm augment (of
the same material) positioned superiorly. The augment was cemented
to the cup and the composite structure was implanted into the
acetabulum and secured with multiple screws. The remaining portion
of the superior defect was packed with morsellized bone allograft
obtained from the bone bank. A polyethylene liner was cemented
into the shell, a new femoral head was impacted onto the trunnion,
the hip was relocated, and the wound was closed in the usual fashion.
Postoperatively, the patient has done well, with good relief of
his hip pain. Postoperative radiographs (Figures 3,4) show the
acetabular cup, superior augment, and screws to be intact, with
evidence of incorporation of the bone graft.

Figure 3 |

Figure 4 |
Case
Discussion
In
this case, a grossly loose acetabular component with a large bony
defect presented a challenging reconstructive problem. A jumbo
acetabular cup with modular augment provided an alternative solution
to using a structural allograft or a cage, with a successful outcome
as of the patients most recent follow-up visit.
References
- Berry
DJ, Müller, ME. Revision arthroplasty using an anti-protrusio
cage for massive acetabular bone deficiency. J Bone Joint
Surg [Br] 74-B:711-715 (1992).
- Bobyn
JD, Stackpool GJ, Hacking SA, Tanzer M, Krygier JJ. Characteristics
of bone ingrowth and interface mechanics of a new porous tantalum
biomaterial. J Bone Joint Surg [Br] 81-B:907-914 (1999).
- Bobyn
JD, Toh K-K, Hacking SA, Tanzer M, Krygier JJ. Tissue response
to porous tantalum acetabular cups: A canine model.
Clin Orthop Rel Res 298:147-155 (1994).
- D'Antonio
JA, Capello WN, Borden LS, Bargar WL, Bierbaum BF, Boettcher
WG, Steinberg ME, Stulberg SD, 'wedge JH. Classification and
management of acetabular abnormalities in total hip arthrplasty.
Clin Orthop Rel Res 243:126-137 (1989).
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JT, Shen FH, Brown TE. The fate of stable femoral components
retained during isolated acetabular revision. J Bone Joint Surg[Am]
84-A:250-255 (2002).
- Paprosky
WG, Magnus RE. Principles of bone grafting in revision total
hip arthroplasty. Acetabular technique. Clin Orthop Rel Res
298:147-155 (1994).
- Paprosky
WG, Perona PG, Lawrence JM.
Acetabular defect classification and surgical reconstruction
in revision arthroplasty: A
6-year follow-up evaluation.
J Arthroplasty 9:33-44 (1994).
- Zardiackas
LD, Parsell DE, Dillon LD, Mitchell DW, Nunnery LA, Poggie R. Structure, metallurgy, and mechanical properties
of a porous tantalum foam. J Biomed Mater Res 58:180-187 (2001).
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